Chemometrics and its Application in Pharmaceutical Field
نویسندگان
چکیده
Chemometrics is the application of statistical and mathematical methods to analytical data to permit maximum collection and extraction of useful information. It is a data-driven interdisciplinary science suitable for solving diverse applications. This review focuses mainly on various chemometric models used and their applications in the pharmaceutical sciences.
منابع مشابه
Application of Chemometrics in Simultaneous Spectrophotometric Quantification of Etophylline and Theophylline: The Drugs with Same Chromophore
Chemometric techniques in spectral analysis have gained importance in the quality control of the drugs mixtures and pharmaceutical formulations containing two or more drugs with overlapping spectra. Since theophylline and etophylline have common chromophore, they cannot be analyzed simultaneously using conventional UV methods. Simultaneous spectrophotometric determination of etophylline and th...
متن کاملChemometrics: A new scenario in herbal drug standardization
Chromatography and spectroscopy techniques are the most commonly used methods in standardization of herbal medicines but the herbal system is not easy to analyze because of their complexity of chemical composition. Many cutting-edge analytical technologies have been introduced to evaluate the quality of medicinal plants and significant amount of measurement data has been produced. Chemometric t...
متن کاملCoupling Chemometrics and NIR Spectroscopy for Food and Drug Authentication
Different examples of successive coupling of Near Infrared Spectroscopy and chemometric for solving problems of authentication and quality control of food and drug samples will be presented. In particular, topics as the traceability of PDO products, the determination of nutritional value of cereals and the quantification of enantiopurity of pharmaceutical API will be discussed.
متن کاملNovel Application of Near-infrared Spectroscopy and Chemometrics Approach for Detection of Lime Juice Adulteration
The aim of this study is to investigate the novel application of a handheld near infra-red spectrophotometer coupled with classification methodologies as a screening approach in detection of adulterated lime juices. For this purpose, a miniaturized near infra-red spectrophotometer (Tellspec®) in the spectral range of 900–1700 nm was used. Three diffuse reflectance spectra of 31 pure...
متن کاملNovel Application of Near-infrared Spectroscopy and Chemometrics Approach for Detection of Lime Juice Adulteration
The aim of this study is to investigate the novel application of a handheld near infra-red spectrophotometer coupled with classification methodologies as a screening approach in detection of adulterated lime juices. For this purpose, a miniaturized near infra-red spectrophotometer (Tellspec®) in the spectral range of 900–1700 nm was used. Three diffuse reflectance spectra of 31 pure...
متن کامل